Article Abstract

An alternative way to initiate Notch1 signaling in non-small cell lung cancer

Authors: Yi-Lin Yang, David Jablons, Liang You

Abstract

Non-small cell lung cancer (NSCLC) cells activate Notch1 signaling to promote cell proliferation and facilitate their survival. It now emerges that endothelial Delta-like ligand 4 (Dll4) may mediate Notch1 activation and inhibit tumor cell growth.

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